Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts Academic Article Article uri icon

Overview

MeSH Major

  • Carcinoma, Squamous Cell
  • Vulvar Neoplasms
  • cdc25 Phosphatases

abstract

  • Human cultures derived after mouse xenografting frequently contain and release highly infectious xenotropic MLV viruses. Laboratories working with xenograft-derived human cultures should be aware of the risk of contamination with potentially biohazardous human-tropic mouse viruses and their horizontal spread to other cultures.

publication date

  • October 2011

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.4161/cbt.12.7.15955

PubMed ID

  • 21750403

Additional Document Info

start page

  • 617

end page

  • 28

volume

  • 12

number

  • 7