Neuroethics, neuroimaging, and disorders of consciousness: promise or peril? Review uri icon


MeSH Major

  • Brain
  • Brain Mapping
  • Consciousness
  • Diagnostic Imaging
  • Diagnostic Techniques, Neurological
  • Unconsciousness


  • The advent of powerful neuroimaging tools such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) has begun to redefine how we diagnose, define, and understand disorders of consciousness such as the vegetative and minimally conscious states. In my paper, I review how research using these methods is both elucidating these brain states and creating diagnostic dilemmas related to their classification as the specificity and sensitivity of traditional behavior-based assessments are weighed against sensitive but not yet fully validated neuroimaging data. I also consider how these methods are being studied as potential communication vectors for therapeutic use in subjects who heretofore have been thought to be unresponsive or minimally conscious. I conclude by considering the ethical challenges posed by novel diagnostic and therapeutic neuroimaging applications and contextualize these scientific developments against the broader needs of patients and families touched by severe brain injury.

publication date

  • October 4, 2011



  • Review



  • eng

PubMed Central ID

  • PMC3116331

PubMed ID

  • 21686236

Additional Document Info

start page

  • 336

end page

  • 46


  • 122