The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models Academic Article uri icon

Overview

MeSH Major

  • Capillaries
  • Diabetes Mellitus, Experimental
  • Diabetic Retinopathy
  • Retinal Vessels
  • Sphingomyelin Phosphodiesterase

abstract

  • This is the first study demonstrating activation of ASM in the retinal vasculature of diabetic retinopathy animal models. Inhibition of ASM could be further explored as a potential therapeutic strategy in treating diabetic retinopathy.

publication date

  • September 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3161322

Digital Object Identifier (DOI)

  • 10.2337/db10-0550

PubMed ID

  • 21771974

Additional Document Info

start page

  • 2370

end page

  • 8

volume

  • 60

number

  • 9