Recurrence and survival in patients undergoing sentinel lymph node biopsy for Merkel cell carcinoma: Analysis of 153 patients from a single institution
Carcinoma, Merkel Cell
Neoplasm Recurrence, Local
SLNB identifies occult nodal metastases in 29% of patients with localized MCC. Predictors of SLNB positivity are tumor size and presence of lymphovascular invasion (LVI). Patients with SLNB-positive disease are more likely to receive further treatment; however, sentinel lymph node (SLN) status is not associated with recurrence or survival. In contrast, LVI is strongly associated with both recurrence and survival.