Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets Academic Article uri icon

Overview

MeSH Major

  • Dendritic Cells
  • Dermatitis, Atopic
  • Psoriasis
  • Skin
  • T-Lymphocyte Subsets

abstract

  • Our results suggest that DC polarity does not directly drive differential T-cell subset responses. Alternatively, disease-specific chemokines might recruit specific memory T-cell subsets into the skin, which in turn might be activated and expanded by DCs at the site of inflammation, maintaining differential immune polarity in these diseases.

publication date

  • September 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jaci.2011.05.016

PubMed ID

  • 21704361

Additional Document Info

start page

  • 574

end page

  • 82.e1-12

volume

  • 128

number

  • 3