Germline PALB2 mutation analysis in breast-pancreas cancer families Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Germ-Line Mutation
  • Nuclear Proteins
  • Pancreatic Neoplasms
  • Tumor Suppressor Proteins

abstract

  • Mutations within the PALB2 gene are rare events that do not account for a substantial proportion of cancer susceptibility in breast-pancreas cancer families. Routine screening of breast-pancreas cancer families for the presence of PALB2 mutations appears to be low yield.

publication date

  • August 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1136/jmg.2010.087379

PubMed ID

  • 21415078

Additional Document Info

start page

  • 523

end page

  • 5

volume

  • 48

number

  • 8