Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept
Recombinant Fusion Proteins
Vascular Endothelial Growth Factor A
These data suggest that decreases in VEGF posttreatment are associated with radiographic response to aflibercept. Elevated baseline chemokines of monocyte lineage in responding patients supports a role for myeloid cells and chemokines as potential biomarkers and regulators of glioma angiogenesis.