Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • Glioblastoma
  • Recombinant Fusion Proteins
  • Vascular Endothelial Growth Factor A

abstract

  • These data suggest that decreases in VEGF posttreatment are associated with radiographic response to aflibercept. Elevated baseline chemokines of monocyte lineage in responding patients supports a role for myeloid cells and chemokines as potential biomarkers and regulators of glioma angiogenesis.

publication date

  • July 15, 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3139700

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-11-0271

PubMed ID

  • 21632852

Additional Document Info

start page

  • 4872

end page

  • 81

volume

  • 17

number

  • 14