MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of bax and maintenance of survivin Academic Article uri icon

Overview

MeSH Major

  • Antigens, Neoplasm
  • Apoptosis
  • Gene Expression Regulation, Neoplastic
  • Inhibitor of Apoptosis Proteins
  • Multiple Myeloma
  • Neoplasm Proteins
  • bcl-2-Associated X Protein

abstract

  • These data support a role for MAGE-A in the pathogenesis and progression of multiple myeloma by inhibiting apoptosis in proliferating myeloma cells through two novel mechanisms.

publication date

  • July 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3131419

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-10-1820

PubMed ID

  • 21565982

Additional Document Info

start page

  • 4309

end page

  • 19

volume

  • 17

number

  • 13