Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: A proteomic approach Academic Article uri icon

Overview

MeSH Major

  • Autoantibodies
  • Autoantigens
  • Endothelial Cells
  • Giant Cell Arteritis
  • Muscle, Smooth, Vascular
  • Proteomics

abstract

  • IgG antibodies to proteins in the proteome of ECs and VSMCs are present in the sera of GCA patients and recognise cellular targets that play key roles in cell biology and maintenance of homeostasis. Their potential pathogenic role remains to be determined.

publication date

  • June 28, 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3218922

Digital Object Identifier (DOI)

  • 10.1186/ar3388

PubMed ID

  • 21711540

Additional Document Info

start page

  • R107

volume

  • 13

number

  • 3