Synchronous epithelial and neuroendocrine cancers of the pancreas: Case series of a rare occurrence Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Pancreatic Ductal
  • Neoplasms, Multiple Primary
  • Neuroendocrine Tumors
  • Pancreatic Neoplasms

abstract

  • The presence of neuroendocrine cells in adenocarcinomas is not an unusual finding and is well described in gastrointestinal tract cancers, eg, colorectal cancer and gastric cancer. Genetic analysis of such tumors has suggested a common multipotent progenitor stem cell origin. The prognostic significance of neuroendocrine cells in adenocarcinoma cells is unclear. There is a scant literature on synchronous pancreas ductal adenocarcinoma and pancreas neuroendocrine tumors. We report 2 cases with a purpose of discussing management strategies, prognosis, and potential etiologies of this rare presentation.

publication date

  • January 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.clcc.2011.03.013

PubMed ID

  • 21859569

Additional Document Info

start page

  • 146

end page

  • 50

volume

  • 10

number

  • 2