mRNA expression signature of gleason grade predicts lethal prostate cancer Academic Article uri icon

Overview

MeSH Major

  • Gene Expression Profiling
  • Prostatic Neoplasms

abstract

  • Our expression signature and the genes identified may improve our understanding of the de-differentiation process of prostate tumors. Additionally, the signature may have clinical applications among men with Gleason 7, by further estimating their risk of lethal prostate cancer and thereby guiding therapy decisions to improve outcomes and reduce overtreatment.

publication date

  • June 10, 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3107753

Digital Object Identifier (DOI)

  • 10.1200/JCO.2010.32.6421

PubMed ID

  • 21537050

Additional Document Info

start page

  • 2391

end page

  • 6

volume

  • 29

number

  • 17