Viperin turns coat in cytomegalovirus infection
Tumor Suppressor Protein p53
Cytomegalovirus infection is associated with cytoskeletal alterations and cell swelling (cytomegaly), which have been attributed to the viral mitochondria-localized inhibitor of apoptosis (vMIA) protein. In a recent issue of Science, Seo et al. (2011) showed that the antiviral host protein viperin is co-opted to function with vMIA for facilitating infection.