Targeted cancer therapies Editorial Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Molecular Targeted Therapy
  • Neoplasms

abstract

  • With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an overview on successful targeted cancer drugs on the market and those drugs that are in late clinical development stages. Importantly, the article lays out main challenges in developing molecular targeted therapies and potential path forward to overcome these challenges, as well as opportunities for China in this new era of targeted agents. The editorial serves as an introduction to the Targeted Cancer Therapies series that will review in depth of major pathways and drugs targeting these pathways to be published in the coming issues of the Chinese Journal of Cancer.

publication date

  • April 22, 2011

Research

keywords

  • Editorial

Identity

Language

  • eng

PubMed Central ID

  • PMC4012258

PubMed ID

  • 21192839

Additional Document Info

start page

  • 1

end page

  • 4

volume

  • 30

number

  • 1