Hypofractionated dose-painting intensity modulated radiation therapy with chemotherapy for nasopharyngeal carcinoma: A prospective trial Academic Article uri icon

Overview

MeSH Major

  • Radiotherapy, Intensity-Modulated

abstract

  • Preliminary findings using a hypofractionated DP-IMRT regimen demonstrated that local control, freedom from distant metastases, and overall survival compared favorably with other series of IMRT and chemotherapy. The highly conformal boost to the tumor bed resulted low rates of severe ototoxicity (Grade 3-4). However, the incidence of in-field brain radiation necrosis indicates that 2.34 Gy per fraction is not safe in this setting.

publication date

  • May 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2952060

Digital Object Identifier (DOI)

  • 10.1016/j.ijrobp.2010.01.026

PubMed ID

  • 20605352

Additional Document Info

start page

  • 148

end page

  • 53

volume

  • 80

number

  • 1