Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice Academic Article uri icon

Overview

MeSH Major

  • Insulin-Secreting Cells
  • Islets of Langerhans Transplantation

abstract

  • Glucose is a mitogenic stimulus for transplanted human beta cells in vivo. Investigating the underlying pathways may point to mechanisms capable of expanding human beta cell mass in vivo.

publication date

  • March 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3034833

Digital Object Identifier (DOI)

  • 10.1007/s00125-010-1919-1

PubMed ID

  • 20936253

Additional Document Info

start page

  • 572

end page

  • 82

volume

  • 54

number

  • 3