Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma Academic Article uri icon


MeSH Major

  • Bordetella Infections
  • Bordetella bronchiseptica
  • Brain Neoplasms
  • Dacarbazine
  • Glioblastoma
  • Respiratory Tract Infections
  • Zoonoses


  • Bordetella bronchiseptica is a gram negative coccobacillus that can be transmitted from domestic animals and cause severe infections in immunocompromised patients. A 56-year-old man with a left parietal glioblastoma was treated with resection, radiation and concomitant and adjuvant temozolomide chemotherapy. He received bevacizumab for progression, and dose dense metronomic temozolomide was added for additional progression. He developed chronic cough and was diagnosed with B. bronchiseptica infection. This is the first reported case of B. bronchiseptica infection in a patient receiving temozolomide. The infection was likely acquired from an infected kitten. Patients receiving temozolomide should be counseled on the risks of acquiring zoonotic infections, including B. bronchiseptica, from their pets.

publication date

  • April 2011



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1007/s11060-010-0322-6

PubMed ID

  • 20676728

Additional Document Info

start page

  • 335

end page

  • 9


  • 102


  • 2