An overview of the diagnostic and therapeutic use of monoclonal antibodies in medicine Review uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Infection
  • Inflammation

abstract

  • Monoclonal antibodies, which include murine, chimeric, humanized and fully human antibodies, bind to their target receptors with high affinity and specificity. In the last two decades several different monoclonal antibodies have been approved by the Food and Drug Administration for therapeutic purposes, and some of these and others have also been radiolabelled for diagnostic and therapeutic purposes. This field is in continuous evolution and this overview highlights the role of radiolabelled antibodies in research and clinical setting.

publication date

  • December 2010

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 21221066

Additional Document Info

start page

  • 574

end page

  • 81

volume

  • 54

number

  • 6