Genetics of the myeloproliferative neoplasms Review uri icon

Overview

MeSH Major

  • Genetic Predisposition to Disease
  • Myeloproliferative Disorders

abstract

  • The spectrum of genetic abnormalities found in the classic MPNs has increased over the last 6 years and somatic mutations in JAK2, MPL, LNK, TET2, EZH2, ASXL1, and IDH1/2 have all been described. Despite this, the initiating genetic events responsible for the development of MPNs is still not totally understood.

publication date

  • March 2011

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/MOH.0b013e328343998e

PubMed ID

  • 21307773

Additional Document Info

start page

  • 117

end page

  • 23

volume

  • 18

number

  • 2