Mechanisms of lymphatic regeneration after tissue transfer
Academic Article
Overview
MeSH Major
Lymphatic System
Lymphatic Vessels
Regeneration
abstract
Our studies suggest that lymphatic regeneration after tissue transfer occurs by ingrowth of lymphatic vessels and spontaneous re-connection of existing lymphatics. This process is temporally and spatially associated with VEGF-C expression and macrophage infiltration. Finally, tissue transfer can be used to bypass damaged lymphatics and promote rapid lymphatic regeneration.