Strategic lessons from the clinical event classification process for the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Cardiovascular Agents
  • Myocardial Infarction
  • Randomized Controlled Trials as Topic
  • Single-Chain Antibodies

abstract

  • A complementary approach of a computerized assessment and physician review was used in the CEC effort of the APEX-AMI trial. The algorithm categorized approximately one third of suspected CHF/cardiogenic shock events. The APEX-AMI CEC experience shows that an algorithmic approach may be a useful strategy for end point evaluation but requires validation.

publication date

  • March 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.cct.2010.12.013

PubMed ID

  • 21220052

Additional Document Info

start page

  • 178

end page

  • 87

volume

  • 32

number

  • 2