Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: The HyperGEN study
DNA Copy Number Variations
Polymorphism, Single Nucleotide
The regions we discovered are candidates for future studies on cardiovascular outcomes, particularly in African Americans. The methods we employed can also provide an outline for genetic researchers interested in jointly testing SNP and CNV effects and/or applying mixed model procedures on a genome-wide scale.