Infectious chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma Academic Article uri icon

Overview

MeSH Major

  • Asthma
  • Chlamydophila Infections
  • Chlamydophila pneumoniae
  • Interleukin-8
  • Neutrophils
  • Respiratory System

abstract

  • Children with asthma who were PCR-positive for C. pneumoniae demonstrated elevated concentrations of IL-8 and neutrophils in BAL fluid compared with similar patients who were positive for C. trachomatis or Mycoplasma organisms, but PCR-negative for C. pneumoniae. Undiagnosed C. pneumoniae infection in children may therefore contribute to poorly controlled asthma via induction of IL-8.

publication date

  • December 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/INF.0b013e3181eaebdc

PubMed ID

  • 21155094

Additional Document Info

start page

  • 1093

end page

  • 8

volume

  • 29

number

  • 12