Alpha 1-antitrypsin deficiency-related alleles Z and S and the risk of Wegener's granulomatosis Academic Article uri icon

Overview

MeSH Major

  • Alleles
  • Genetic Predisposition to Disease
  • Granulomatosis with Polyangiitis
  • alpha 1-Antitrypsin

abstract

  • Both Z and S alleles display associations with risk of WG in a codominant genetic pattern. These findings strengthen the evidence of a causal link between α(1) AT deficiency and susceptibility to WG.

publication date

  • December 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3123032

Digital Object Identifier (DOI)

  • 10.1002/art.27742

PubMed ID

  • 20827781

Additional Document Info

start page

  • 3760

end page

  • 7

volume

  • 62

number

  • 12