Hepatitis B virus-DNA level and basal core promoter A1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Hepatocellular
  • DNA, Viral
  • Hepatitis B Core Antigens
  • Hepatitis B Surface Antigens
  • Liver
  • Liver Neoplasms

abstract

  • The amount of HBV-DNA in liver tissue and the presence of the basal core promoter mutation were two independent predictors for postoperative survival in HCC. A short stretch pre-S deletion located between codons 107 and 141 was strongly associated with a poorer postoperative prognosis.

publication date

  • December 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/hep.23898

PubMed ID

  • 20814897

Additional Document Info

start page

  • 1922

end page

  • 33

volume

  • 52

number

  • 6