Rapid-learning system for cancer care Article uri icon


MeSH Major

  • Delivery of Health Care, Integrated
  • Evidence-Based Medicine
  • Neoplasms
  • Precision Medicine
  • Quality of Health Care


  • Compelling public interest is propelling national efforts to advance the evidence base for cancer treatment and control measures and to transform the way in which evidence is aggregated and applied. Substantial investments in health information technology, comparative effectiveness research, health care quality and value, and personalized medicine support these efforts and have resulted in considerable progress to date. An emerging initiative, and one that integrates these converging approaches to improving health care, is "rapid-learning health care." In this framework, routinely collected real-time clinical data drive the process of scientific discovery, which becomes a natural outgrowth of patient care. To better understand the state of the rapid-learning health care model and its potential implications for oncology, the National Cancer Policy Forum of the Institute of Medicine held a workshop entitled "A Foundation for Evidence-Driven Practice: A Rapid-Learning System for Cancer Care" in October 2009. Participants examined the elements of a rapid-learning system for cancer, including registries and databases, emerging information technology, patient-centered and -driven clinical decision support, patient engagement, culture change, clinical practice guidelines, point-of-care needs in clinical oncology, and federal policy issues and implications. This Special Article reviews the activities of the workshop and sets the stage to move from vision to action.

publication date

  • September 20, 2010



  • Article



  • eng

PubMed Central ID

  • PMC2953977

Digital Object Identifier (DOI)

  • 10.1200/JCO.2010.28.5478

PubMed ID

  • 20585094

Additional Document Info

start page

  • 4268

end page

  • 74


  • 28


  • 27