Insulin-like growth factor-1 receptor and phosphorylated AKT-serine 473 expression in 132 resected thymomas and thymic carcinomas Academic Article uri icon

Overview

MeSH Major

  • Oncogene Protein v-akt
  • Receptor, IGF Type 1
  • Thymoma
  • Thymus Neoplasms

abstract

  • The current retrospective analysis demonstrated that disease stage, tumor histology, sex, and resection type were major prognostic factors in the survival of patients with thymic malignancies. The expression levels of IGF-1R and p-AKT in thymic tumors suggested that IGF-1R is a potential target for treatment.

publication date

  • December 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3057766

Digital Object Identifier (DOI)

  • 10.1002/cncr.25367

PubMed ID

  • 20597130

Additional Document Info

start page

  • 4686

end page

  • 95

volume

  • 116

number

  • 20