Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation Academic Article uri icon

Overview

MeSH Major

  • Cell Transformation, Neoplastic
  • Interleukin-6
  • Mammary Neoplasms, Animal
  • STAT3 Transcription Factor
  • ras GTPase-Activating Proteins

abstract

  • The cellular and environmental context can lead to differential IL-6/pStat3 signaling and a dependency on this cytokine and transcription factor for migration, invasion and tumorigenesis.

publication date

  • October 7, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3096973

Digital Object Identifier (DOI)

  • 10.1186/bcr2725

PubMed ID

  • 20929542

Additional Document Info

start page

  • R80

volume

  • 12

number

  • 5