Human epidermal growth factor receptor 2 expression status provides independent prognostic information in patients with urothelial carcinoma of the urinary bladder
Academic Article
Overview
MeSH Major
Cystectomy
Neoplasm Recurrence, Local
Receptor, ErbB-2
Urinary Bladder Neoplasms
abstract
a positive HER-2 status is associated with aggressive UCB and provides independent prognostic information for UCB recurrence and mortality. Assessment of HER-2 status can be used to identify patients at high risk of disease progression who may benefit from adjuvant HER-2-targeted mono- or combined therapy after RC.
