Genetic analysis of the early natural history of epithelial ovarian carcinoma Academic Article uri icon

Overview

MeSH Major

  • Carcinoma
  • Gene Expression Regulation, Neoplastic
  • Ovarian Neoplasms
  • Precancerous Conditions

abstract

  • Together, these data indicate that EOC frequently arises in ovarian cystic inclusions, is preceded by an identifiable dysplastic precursor lesion, and that increased cell proliferation, decreased apoptosis, and aneuploidy are likely to represent very early aberrations in ovarian tumorigenesis.

publication date

  • September 14, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2859950

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0010358

PubMed ID

  • 20436685

Additional Document Info

start page

  • e10358

volume

  • 5

number

  • 4