SaporinToxin-conjugated monoclonal antibody targeting prostate-specific membrane antigen has potent anticancer activity Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antineoplastic Agents, Phytogenic
  • Prostate-Specific Antigen
  • Prostatic Neoplasms
  • Ribosome Inactivating Proteins, Type 1

abstract

  • Our findings show that hJ591-SAZAP conjugate has potent and selective antitumor effects on PSMA-positive PC cells in vitro and in vivo. This study supports development of PSMA antibody-toxin conjugates for therapy of PC.

publication date

  • September 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/pros.21164

PubMed ID

  • 20623630

Additional Document Info

start page

  • 1286

end page

  • 94

volume

  • 70

number

  • 12