Inherited predisposition to cancer: Introduction and overview Review uri icon

Overview

MeSH Major

  • Genetic Predisposition to Disease
  • Neoplastic Syndromes, Hereditary

abstract

  • The past three decades have witnessed an explosion in information regarding the genetic mutations underlying predisposition to common malignancies. Discoveries are now being made regarding genomic variants associated with disease risk for, and outcome following, treatment for cancer. Responsible translation of these discoveries to medical practice requires attention to principles of clinical utility as well as social and ethical aspects.

publication date

  • October 2010

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2010.06.005

PubMed ID

  • 20816574

Additional Document Info

start page

  • 793

end page

  • 7

volume

  • 24

number

  • 5