Human motor evoked potential responses following spinal cord transection: An in vivo study Academic Article uri icon


MeSH Major

  • Evoked Potentials, Motor
  • Meningomyelocele
  • Monitoring, Intraoperative
  • Neurosurgical Procedures
  • Spinal Cord


  • Motor evoked potential (MEP) monitoring has been used increasingly in conjunction with somatosensory evoked potential monitoring to monitor neurological changes during complex spinal operations. No published report has demonstrated the effects of segmental spinal cord transection on MEP monitoring. The authors describe the case of an 11-year-old girl with lumbar myelomeningocele and worsening thoracolumbar scoliosis who underwent a T11-L5 fusion and spinal transection to prevent tethering. Intraoperative MEP and somatosensory evoked potential monitoring were performed, and the spinal cord was transected in 4 quadrants. The MEPs were lost unilaterally as each anterior quadrant was sectioned. This is the first reported case that demonstrates the link between spinal cord transection and MEP signaling characteristics. Furthermore, it demonstrates the relatively minor input of the ipsilateral ventral corticospinal tract in MEP physiology at the thoracolumbar junction. Finally, this study further supports the use of MEPs as a specific intraoperative neuromonitoring tool.

publication date

  • July 2010



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.3171/2010.3.FOCUS09201

PubMed ID

  • 20594002

Additional Document Info

start page

  • E4


  • 29


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