HLA B*44: Protective effects in MS susceptibility and MRI outcome measures Academic Article uri icon

Overview

MeSH Major

  • Genetic Predisposition to Disease
  • HLA-B Antigens
  • Magnetic Resonance Imaging
  • Multiple Sclerosis

abstract

  • The MHC class I alleles HLA A*02 and HLA B*44 independently reduce susceptibility to MS, but only HLA B*44 appears to influence disease course, preserving brain volume and reducing the burden of T2 hyperintense lesions in subjects with MS.

publication date

  • August 17, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2931768

Digital Object Identifier (DOI)

  • 10.1212/WNL.0b013e3181ed9c9c

PubMed ID

  • 20713950

Additional Document Info

start page

  • 634

end page

  • 40

volume

  • 75

number

  • 7