Anti-60-kDa heat shock protein antibodies in fetal serum: A biomarker for unexplained small for gestational age fetuses Academic Article uri icon

Overview

MeSH Major

  • Antibodies
  • Chaperonin 60
  • Fetal Blood
  • Fetal Weight
  • Gestational Age

abstract

  • Fetuses with unexplained SGA are positive for IgM and IgG antibody to human HSP60 and the specific IgM antibody level is predictive of fetal mortality. Detection of these antibodies indicates that a placental perturbation and a fetal autoimmune reaction to HSP60 are associated with this developmental delay.

publication date

  • November 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1159/000314021

PubMed ID

  • 21051851

Additional Document Info

start page

  • 299

end page

  • 305

volume

  • 70

number

  • 4