Assessing the human immune system through blood transcriptomics Review uri icon

Overview

MeSH Major

  • Biomarkers
  • Gene Expression Profiling
  • Immune System

abstract

  • Blood is the pipeline of the immune system. Assessing changes in transcript abundance in blood on a genome-wide scale affords a comprehensive view of the status of the immune system in health and disease. This review summarizes the work that has used this approach to identify therapeutic targets and biomarker signatures in the field of autoimmunity and infectious disease. Recent technological and methodological advances that will carry the blood transcriptome research field forward are also discussed.

publication date

  • July 2010

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC2895587

Digital Object Identifier (DOI)

  • 10.1186/1741-7007-8-84

PubMed ID

  • 20619006

Additional Document Info

start page

  • 84

volume

  • 8