Incidence and time course of bleeding after long-term amenorrhea after breast cancer treatment: A prospective study
Antineoplastic Combined Chemotherapy Protocols
A considerable proportion of women treated with chemotherapy will experience periods of CIA, but many will resume bleeding. Newer treatment regimens such as ACT appear to have a higher resumption of bleeding compared with CMF. This finding may have implications for choice of anti-estrogen treatment and for future potential pregnancies/fertility.