Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcome after tissue plasminogen activator treatment in stroke Academic Article uri icon

Overview

MeSH Major

  • Amine Oxidase (Copper-Containing)
  • Cell Adhesion Molecules
  • Intracranial Hemorrhages
  • Nervous System Diseases
  • Stroke
  • Tissue Plasminogen Activator

abstract

  • Our data demonstrate that baseline VAP-1/SSAO activity predicts parenchymal hemorrhage after tPA, suggesting the safety of thrombolytic agents could be improved by considering VAP-1/SSAO activity. Furthermore, anti-VAP-1/SSAO drugs given with tPA may prevent neurological worsening in patients with ischemic stroke.

publication date

  • July 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/STROKEAHA.110.584623

PubMed ID

  • 20538694

Additional Document Info

start page

  • 1528

end page

  • 35

volume

  • 41

number

  • 7