Adverse events after stopping clopidogrel in post-acute coronary syndrome patients insights from a large integrated healthcare delivery system
Acute Coronary Syndrome
Platelet Aggregation Inhibitors
We observed a clustering of adverse events in the 0 to 90 days after stopping clopidogrel. This clustering of events was not present among patients stopping ACE inhibitors. These findings are consistent with a possible rebound platelet hyper-reactivity after stopping clopidogrel and additional platelet studies are needed to confirm this effect.