Methylenedioxymethamphetamine inhibits mitochondrial complex i activity in mice: A possible mechanism underlying neurotoxicity Academic Article uri icon

Overview

MeSH Major

  • Electron Transport Complex I
  • Hallucinogens
  • N-Methyl-3,4-methylenedioxyamphetamine
  • Neurotoxicity Syndromes

abstract

  • Inhibition of mitochondrial complex I following MDMA could be the source of free radicals responsible for oxidative stress and the consequent neurotoxicity of this drug in mice.

publication date

  • May 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2874846

Digital Object Identifier (DOI)

  • 10.1111/j.1476-5381.2010.00663.x

PubMed ID

  • 20423338

Additional Document Info

start page

  • 233

end page

  • 45

volume

  • 160

number

  • 2