Deletion of CD39 on natural killer cells attenuates hepatic ischemia/reperfusion injury in mice Academic Article uri icon

Overview

MeSH Major

  • Apyrase
  • Killer Cells, Natural
  • Reperfusion Injury

abstract

  • We propose that CD39 deficiency and changes in P2 receptor activation abrogate secretion of interferon gamma by NK cells in response to inflammatory mediators, thereby limiting tissue damage mediated by these innate immune cells during IRI.

publication date

  • May 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2903010

Digital Object Identifier (DOI)

  • 10.1002/hep.23510

PubMed ID

  • 20146261

Additional Document Info

start page

  • 1702

end page

  • 11

volume

  • 51

number

  • 5