The influence of margin width and volume of disease near margin on benefit of radiation therapy for women with DCIS treated with breast-conserving therapy
Carcinoma, Intraductal, Noninfiltrating
Effect of RT on IBTR risk is influenced by both margin width and number of involved ducts at nearest margin. Patients with higher volume of disease near the margin derive a greater benefit from the addition of RT. Despite margins of >or=10 mm, the risk of IBTR remains substantial in patients with DCIS.