Progress in aromatase research and identification of key future directions Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents, Hormonal
  • Aromatase
  • Aromatase Inhibitors
  • Neoplasms

abstract

  • The IX International Aromatase Conference focused upon key developments in research related to the aromatase enzyme that had occurred since the last meeting. A session took place at the conclusion of conference discussing key areas for future research and issues currently facing researchers in the field. While significant progress on understanding structural elements of the enzyme and regulatory mechanisms of both the gene and protein provides an excellent basis for development of improved aromatase inhibitors and exploration of the important problem of aromatase inhibitor resistance, significant challenges remain. Increasing the speed with which findings are translated into clinical practice and finding an appropriate balance between basic and translational research were identified as areas which require further attention before the next meeting in 2010.

publication date

  • February 28, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jsbmb.2009.09.005

PubMed ID

  • 19778609

Additional Document Info

start page

  • 311

end page

  • 5

volume

  • 118

number

  • 4-5