Effect of blood flow on double inversion recovery vessel wall MRI of the peripheral arteries: Quantitation with T2 mapping and comparison with flow-insensitive T2-prepared inversion recovery imaging Academic Article uri icon


MeSH Major

  • Arteries
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Angiography


  • Blood suppression in the lower extremities using flow-reliant methods such as double inversion recovery may be problematic due to slow blood flow. T(2) mapping using fast spin echo (FSE) acquisition was utilized to quantitate the effectiveness of double inversion recovery blood suppression in 13 subjects and showed that 25 +/- 12% of perceived vessel wall pixels in the popliteal arteries contained artifactual blood signal. To overcome this problem, a flow-insensitive T(2)-prepared inversion recovery sequence was implemented and optimal timing parameters were calculated for FSE acquisition. Black blood vessel wall imaging of the popliteal and femoral arteries was performed using two-dimensional T(2)-prepared inversion recovery-FSE in the same 13 subjects. Comparison with two-dimensional double inversion recovery-FSE showed that T(2)-prepared inversion recovery-FSE reduced wall-mimicking blood artifacts that inflated double inversion recovery-FSE vessel wall area measurements in the popliteal artery.

publication date

  • March 2010



  • Academic Article



  • eng

PubMed Central ID

  • PMC2921169

Digital Object Identifier (DOI)

  • 10.1002/mrm.22227

PubMed ID

  • 20187182

Additional Document Info

start page

  • 736

end page

  • 44


  • 63


  • 3