Immunophenotypic Analysis of AIDS-Related Diffuse Large B-Cell Lymphoma and Clinical Implications in Patients from AIDS Malignancies Consortium Clinical Trials 010 and 034 Academic Article uri icon

Overview

MeSH Major

  • Immunophenotyping
  • Ki-67 Antigen
  • Lymphoma, AIDS-Related
  • Lymphoma, Large B-Cell, Diffuse

abstract

  • These data indicate that with current treatment strategies for lymphoma and control of HIV infection, commonly used immunohistochemical markers may not be clinically relevant in HIV-infected patients with DLBCL. The only predictive immunohistochemical marker was found to be Ki-67, where a higher proliferation index was associated with better survival, suggesting a better response to therapy in patients whose tumors had higher proliferation rates.

publication date

  • October 20, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2799056

Digital Object Identifier (DOI)

  • 10.1200/JCO.2008.20.5450

PubMed ID

  • 19752343

Additional Document Info

start page

  • 5039

end page

  • 48

volume

  • 27

number

  • 30