Innate immune cells cast an eye on DNA Academic Article uri icon

Overview

MeSH Major

  • DNA
  • Immunity, Innate
  • Trans-Activators

abstract

  • The threonine phosphatase eyes absent (EYA) has been identified as a novel regulator of innate immune responses to cytosolic nucleic acids and undigested DNA from apoptotic cells. EYA regulates responses of yet unidentified DNA sensors and enhances interferon-beta and CXCL10 transcription.

publication date

  • December 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/jmcb/mjp023

PubMed ID

  • 19789172

Additional Document Info

start page

  • 77

end page

  • 9

volume

  • 1

number

  • 2