Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer Academic Article uri icon

Overview

MeSH Major

  • Carcinoma
  • DNA-Binding Proteins
  • PTEN Phosphohydrolase
  • Prostatic Neoplasms
  • Trans-Activators
  • Transcription Factors

abstract

  • Our data suggest that FISH studies of PTEN gene loss and ERG/ETV1 gene rearrangements could be pursued for patient stratification, selection and hypothesis-generating subgroup analyses in future PCa clinical trials and potentially in patient management.

publication date

  • February 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2837564

Digital Object Identifier (DOI)

  • 10.1038/sj.bjc.6605554

PubMed ID

  • 20104229

Additional Document Info

start page

  • 678

end page

  • 84

volume

  • 102

number

  • 4