Laryngeal neuropathy of Charcot-Marie-Tooth disease: Further observations and novel mutations associated with vocal fold paresis Academic Article uri icon

Overview

MeSH Major

  • Charcot-Marie-Tooth Disease
  • Mutation
  • Vocal Cord Paralysis

abstract

  • The clinical course of the cases suggests slowly progressive neuropathy that appears to be nerve length dependent. The lack of severe respiratory distress despite dense bilateral paresis is consistent with existing reports and with the reported low rate of tracheostomy in adults with laryngeal manifestations of CMT. Genetic testing does not currently inform expectations or management of laryngeal disease. Dyspnea, dysphagia, and OSA symptoms in patients with CMT require careful laryngologic evaluation.

publication date

  • February 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/lary.20685

PubMed ID

  • 19950375

Additional Document Info

start page

  • 291

end page

  • 6

volume

  • 120

number

  • 2