Systemic sclerosis and lupus: Points in an interferon-mediated continuum Academic Article uri icon

Overview

MeSH Major

  • Gene Expression Profiling
  • Interferons
  • Lupus Erythematosus, Systemic
  • Scleroderma, Systemic

abstract

  • SLE and SSc fit within the same spectrum of IFN-mediated diseases. A subset of SSc patients shows a "lupus-like" high IFN-inducible gene expression pattern that correlates with the presence of antitopoisomerase and anti-U1 RNP antibodies.

publication date

  • February 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2879587

Digital Object Identifier (DOI)

  • 10.1002/art.27224

PubMed ID

  • 20112391

Additional Document Info

start page

  • 589

end page

  • 98

volume

  • 62

number

  • 2