Bacterial Invasion: Linking Autophagy and Innate Immunity Academic Article uri icon

Overview

MeSH Major

  • Autophagy
  • Bacterial Infections
  • Immunity, Innate

abstract

  • Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.

publication date

  • February 9, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.cub.2009.12.016

PubMed ID

  • 20144769

Additional Document Info

start page

  • R106

end page

  • 8

volume

  • 20

number

  • 3