Expression of galectin-3 in renal neoplasms Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Renal Cell
  • Galectin 3
  • Kidney Neoplasms

abstract

  • This study confirms that Galactin-3 is strongly overexpressed in renal cell neoplasms of distal tubular differentiation, that is, oncocytoma and chromophobe RCCs, suggesting it might be used as a possible differential diagnostic tool for renal cell neoplasm with oncocytic or granular cells. Furthermore, we observed a strong association of overexpression of Galectin-3 and high nuclear grade in clear cell RCC. These results also suggest a possible pivotal role for Galectin-3 in the differentiation and prognosis of clear cell RCC.

publication date

  • January 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 20073610

Additional Document Info

start page

  • 90

end page

  • 4

volume

  • 134

number

  • 1